Stadium: Admiral Fetterman Field Round: 1
| NCAAF | 2022/12/10 17:00 | Ferris State v West Florida | L | 38-17 |
| NCAAF | 2022/12/03 19:05 | West Florida v Wingate Bulldogs | W | 45-14 |
| NCAAF | 2022/11/26 19:30 | Delta State v West Florida | W | 27-38 |
| NCAAF | 2022/11/19 18:00 | West Florida v Limestone Saints | W | 45-19 |
| NCAAF | 2022/11/12 20:00 | Mississippi College Choctaws v West Florida | W | 21-56 |
| NCAAF | 2022/11/05 23:00 | Valdosta State v West Florida | W | 31-32 |
| NCAAF | 2022/10/29 21:00 | West Florida v West Alabama Tigers | W | 36-24 |
| NCAAF | 2022/10/22 21:00 | West Florida v Mississippi College Choctaws | W | 45-17 |
| NCAAF | 2022/11/12 18:00 | Ashland Eagles v Kentucky Wesleyan | L | 41-10 |
| NCAAF | 2022/11/05 21:00 | Kentucky Wesleyan v Tiffin Dragons | L | 13-72 |
| NCAAF | 2022/10/29 16:00 | Walsh U. Cavaliers v Kentucky Wesleyan | L | 35-10 |
| NCAAF | 2022/10/22 17:00 | Ohio Dominican Panthers v Kentucky Wesleyan | L | 49-7 |
| NCAAF | 2022/10/15 21:00 | Kentucky Wesleyan v Findlay Oilers | L | 7-44 |
| NCAAF | 2022/10/08 18:00 | Quincy v Kentucky Wesleyan | L | 46-9 |
| NCAAF | 2022/10/01 23:00 | Kentucky Wesleyan v Hillsdale Chargers | W | 31-27 |
| NCAAF | 2022/09/24 18:00 | William Jewell College Cardinals v Kentucky Wesleyan | L | 24-17 |