Stadium: F. G. Clark Center
Home Manager: Sean Woods Away Manager: Lindsey Hunter
| NCAAB | 2021/01/18 22:30 | Mississippi Valley State v Southern | L | 61-102 |
| NCAAB | 2020/02/18 01:30 | Mississippi Valley State v Southern | L | 62-95 |
| NCAAB | 2020/01/20 22:00 | Southern v Mississippi Valley State | L | 74-70 |
| NCAAB | 2019/02/19 01:30 | Southern v Mississippi Valley State | W | 59-70 |
| NCAAB | 2019/01/22 01:30 | Mississippi Valley State v Southern | L | 56-80 |
| NCAAB | 2018/02/12 22:00 | Southern v Mississippi Valley State | L | 55-51 |
| NCAAB | 2018/01/16 01:30 | Mississippi Valley State v Southern | L | 70-78 |
| NCAAB | 2017/02/14 01:30 | Mississippi Valley State v Southern | L | 72-81 |
| NCAAB | 2022/01/22 20:00 | Mississippi Valley State v Grambling State | L | 64-68 |
| NCAAB | 2022/01/18 01:30 | Florida A&M v Mississippi Valley State | L | 78-70 |
| NCAAB | 2022/01/15 22:30 | Bethune Cookman v Mississippi Valley State | L | 62-60 |
| NCAAB | 2022/01/11 01:30 | Mississippi Valley State v Texas Southern | L | 58-95 |
| NCAAB | 2022/01/08 23:30 | Mississippi Valley State v Prairie View | W | 84-82 |
| NCAAB | 2022/01/06 01:30 | Alabama A&M v Mississippi Valley State | L | 72-67 |
| NCAAB | 2022/01/03 22:00 | Alabama State v Mississippi Valley State | L | 84-75 |
| NCAAB | 2021/12/23 00:30 | Mississippi Valley State v UAB | L | 58-100 |
| NCAAB | 2022/01/22 23:00 | Arkansas-Pine Bluff v Southern | W | 51-99 |
| NCAAB | 2022/01/15 23:00 | Southern v Grambling State | L | 77-83 |
| NCAAB | 2022/01/11 00:30 | Southern v Bethune Cookman | W | 69-59 |
| NCAAB | 2022/01/08 21:00 | Southern v Florida A&M | W | 80-66 |
| NCAAB | 2022/01/04 01:30 | Texas Southern v Southern | W | 50-63 |
| NCAAB | 2021/12/22 00:00 | Southern v Dayton | L | 60-69 |
| NCAAB | 2021/12/19 22:30 | Southern v Kent State | W | 78-76 |
| NCAAB | 2021/12/11 23:30 | SE Louisiana v Southern | W | 66-72 |